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A larger study is needed to confirm findings of this pilot project in order to recommend the general use of low dose anabolic steroids after joint replacement surgery. CANINE AND FEDERATION OF CANINE ASSOCIATION OF AMERICA The Canine and Federal Association of America (CFAA) funded this study. Dr. Lukaszuk serves as a member of the Board of Directors of CFAA. Dr. Howard Yeh has been the Medical Director of the CFAA. Participants: Patient Sam, Cone-affiliated Canine, most recent surgery September 7th, 2008 Patient Laura, Jack-affiliated Golden Retriever, first surgery May 4th, 2008, second September 3rd, 2008 Surgery participants were given separate progress reports so that they could compare conditions of their dogs at 5 and 10 weeks after the surgery and see how different treatments affected their dogs. This is the first study looking at a wide range of dog breeds after low dose anabolics, so the participants were able to observe effects that vary greatly between breeds. Treatment approach: 6 weeks after surgery, the dogs still on steroids. The protocol is described in the following paragraphs. Platelet drop criterion is performed to assess damage done to bone and remodeling to the implant. Lower platelets and low platelet response indicate that scarring may be returning; more complete data on this will be collected in a later study. AKC Anomaly Checklist (ACL), the canine ACL checklist was given to the owners/keepers. Every dog was checked. More complete data on this will be collected in a later study. Cyclic stress testing, which measures cumulative force to the ACL, was done at 5 weeks. Multiple myeloma features in the history, tests given and family history, may be obtained. The dog is measured using the Golden Standards to mark the results of the genetic tests. Detection and stratification of osteoarthritis were done at the 5 and 10 week follow up visit. Detection and stratification of the myeloma was done at 3 month follow up visit. What findings were achieved? They performed ACL staging. ACL remodeling of the control did not show evidence of scarring. All the dogs showed mild remodeling, but none showed Related Article: